We describe Aspidosperma huberianum, a new species from the Brazilian Amazon. The new taxon is morphologically similar to A. darienense, but can be distinguished readily by characters of the leaf (including venation), flower (including calyx lobe number and indument of the corolla and ovary), pollen, fruit, and seed. We provide a taxonomic description, pollen characterization, illustration, photographs, and a distribution map for the new taxon, as well as information on its conservation status, habitat, and phenology.