Adenocalymma is a genus of Neotropical lianas, shrubs, and treelets that belongs to tribe Bignonieae (Bignoniaceae). The genus is recognized by the cupular trichomes found on the prophylls, bracts, bracteoles, calyces, and fruits, and the presence of articulated petioles and petiolules. A recent molecular phylogeny of Adenocalymma recovered all three species of Neojobertia as well as Pleonotoma albiflora nested within the genus, indicating the need for an updated circumscription. Molecular phylogenetic results combined with morphological data also revealed the need for a revised circumscription for several species. Here, we present an updated circumscription and synopsis of Adenocalymma that recognizes 76 species within the genus. New combinations are proposed for N. alboaurantiaca, N. candolleana, and N. mirabile. Lectotypes are proposed for A. longeracemosum, A. nodosum, and A. validum, a neotype is proposed for A. paucifoliolatum, and an epitype is designated to support the lectoype of A. trifoliatum. In addition, twelve new synonyms are proposed as follows: 1) A. croatii is synonymized under A. biternatum; 2) A. aspericarpum is synonymized under A. cladotrichum; 3) A. fruticosum is synonymized under A. hyposticum; 4) A. apterospermum is synonymized under A. marginatum; 5) A. campicola is synonymized under A. nodosum; (6, 7, 8) A. axillare, A. bipinnatum, and A. paucifoliolatum are synonymized under A. peregrinum; 9) A. involucratum is synonymized under A. pubescens; 10) A. reticulatum is synonymized under A. scabriusculum; 11) A. pseudopatulum is synonymized under A. schomburgkii; and 12) A. prancei is synonymized under A. subincanum.