Sympatry among bobcats (Lynx rufus), coyotes (Canis latrans) and gray foxes (Urocyon cinereoargenteus) is relatively recent in the southeastern United States given recent expansion of coyote range. Interspecific relationships among canids and felids have been documented in northern latitudes. However, interactions among these three species at southern latitudes are poorly understood. We examined overlap in space use of sympatric bobcats (n = 47), coyotes (n = 37) and gray foxes (n = 27) in central Mississippi during 1993–1997. Home ranges of all three species overlapped extensively. However, gray foxes maintained core use areas that did not overlap substantially with those of bobcats and coyotes. Home range and core area overlap were similar across seasons among all species. Our findings indicate that these three species readily share space, but gray foxes apparently maintain core areas in areas void of concentrated bobcat and coyote use.