The Ozark pocket gopher (Geomys bursarius ozarkensis) has recently been described as a new subspecies of the plains pocket gopher (G. bursarius) inhabiting north-central Arkansas and is considered a “species of greatest conservation need” in Arkansas; therefore, research on spatial use and life-history characteristics were conducted via radio telemetry to elucidate home range and mortality. Home range size was associated negatively with adult female body mass, but was positively associated with juvenile body mass. Home range size showed no pattern with either adult or juvenile male mass. Home ranges were significantly larger for females in the winter/spring versus spring/summer probably due to food availability varying with season and the concurrence of the reproductive season in spring. The majority of pocket gopher mortality occurred in the winter months, during the period of increased movement. We documented two sources of mortality for pocket gophers: predation and flooding.