Translator Disclaimer
1 March 2002 Giardia intestinalis Glucosamine 6-Phosphate Isomerase: the Key Enzyme to Encystment Appears to be Controlled by Ubiquitin Attachment
Author Affiliations +
Abstract

The cyst wall of the parasitic protozoan, Giardia intestinalis, is composed of a polymer of N-acetylgalactosamine, the precursor of which is synthesized by an inducible enzyme pathway. The first enzyme in this pathway, glucosamine 6-phosphate isomerase, is transcriptionally regulated. During encystment and in mature cysts this isomerase appears to be modified by ubiquitin attachment. Thus, it might be targeted for destruction by an ubiquitin-mediated pathway, suggesting that glucosamine 6-phosphate isomerase expression is tightly regulated.

ALEX B. LOPEZ, MOHAMMED T. HOSSAIN, and HARRY VAN KEULEN "Giardia intestinalis Glucosamine 6-Phosphate Isomerase: the Key Enzyme to Encystment Appears to be Controlled by Ubiquitin Attachment," The Journal of Eukaryotic Microbiology 49(2), 134-136, (1 March 2002). https://doi.org/10.1111/j.1550-7408.2002.tb00356.x
Received: 20 September 2001; Accepted: 23 December 2001; Published: 1 March 2002
JOURNAL ARTICLE
3 PAGES

This article is only available to subscribers.
It is not available for individual sale.
+ SAVE TO MY LIBRARY

SHARE
ARTICLE IMPACT
RIGHTS & PERMISSIONS
Get copyright permission
Back to Top