Arizona gray squirrels (Sciurus arizonensis) are endemic to the southwestern United States and northwestern Mexico. Despite classification as a species of concern in portions of its range, little is known about Arizona gray squirrels. We investigated survival and causes of mortality for a population of squirrels in the Huachuca Mountains in 2007 and 2008. Adult survival was high and did not differ between sexes, with probability of survival >0.70 one year postcapture. Predation was the most common known cause of mortality; consequently, management plans should account for habitat characteristics that provide protection from predators when managing for Arizona gray squirrels.