Although persistent organic pollutants (POPs) in bottom-feeding fish have been monitored for decades in Kansas, no information regarding long term trends has been published. Therefore, in this study we examined fish tissue data collected from six long-term, large-river, fish tissue monitoring stations in Kansas for trends in POP concentrations. Based on the findings we also forecasted future persistence and discussed the practical implications of our findings. The data we examined consisted of whole-body composited multi-fish samples collected over periods spanning 21–33 years. Common carp was the target species, but occasionally other bottom-feeding species were substituted when necessary. The sample constituents examined were dieldrin, technical chlordane, dichlorodiphenyltrichloroethanes (DDTs), and polychlorinated biphenyls (PCBs). Constituent data were normalized by lipid content prior to analysis, however, because lipid content was not measured during certain time periods, multiple imputation (MI) and analyses techniques (SAS 2014) were employed to overcome the data gaps. The lipidnormalized data were analyzed for time trends using robust non-parametric techniques, which were capable of handling both censored and uncensored data. Because of expected high sample variability, correlations between time and constituent concentrations were considered statistically probable (significant) at p-values < 0.1. Where correlations were significant, the trend line equations were extrapolated to current method reporting limit (RLs) concentrations and 90% prediction intervals (PIs) were constructed around the forecasted RL/year intercepts. Fifteen of the 24 analyses resulted in statistical significance, but no monitoring station experienced significantly declining trends among all four constituents, nor did any constituent significantly decrease across all six stations. The average forecasted RL/year intercept was 2050 (PI = /- 23 years), however some upper PIs suggested some POPS could remain detectable in fish for at least another century.