The Virginia opossum (Didelphis virginiana) is the only marsupial native to the United States. In recent times, D. virginiana has expanded its range through natural movements and anthropogenic introductions. Didelphis virginiana has been present in southern Arizona owing to range expansion by the Mexican subspecies (D. v. californica) and anthropogenic introductions of the eastern subspecies (D. v. virginiana). Here, we document the recent collection of an opossum in central Arizona. We also discuss how it possibly moved there and report on its stomach contents at the time of collection.