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1 June 2011 Chemotherapeutic Treatment for Leukemia in a Bearded Dragon (Pogona vitticeps)
Gwen Jankowski, Jeffrey Sirninger, Jessica Borne, Javier G. Nevarez
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A 4.5-yr-old, captive-bred, male bearded dragon (Pogona vitticeps) presented for lethargy, anorexia, and increased mucoid salivation with upper respiratory clicks. Diagnostics were declined and the bearded dragon was prescribed ceftazidime 20 mg/kg i.m. q 72 hr. The patient presented again 1 wk later with a marked monocytosis, heterophilia, and lymphocytosis, and a clinical diagnosis of chronic monocytic leukemia was made. Chemotherapy with cytosine arabinoside (100 mg/m2 over 48 hr i.v.) was initiated. Forty-four hours into the treatment the dragon became acutely unresponsive and died within 1 hr. Adverse effects as a result of i.v. cytosine arabinoside therapy were not identified despite previous reports suggestive that the drug induces renal failure.

American Association of Zoo Veterinarians
Gwen Jankowski, Jeffrey Sirninger, Jessica Borne, and Javier G. Nevarez "Chemotherapeutic Treatment for Leukemia in a Bearded Dragon (Pogona vitticeps)," Journal of Zoo and Wildlife Medicine 42(2), 322-325, (1 June 2011).
Received: 3 September 2010; Published: 1 June 2011
bearded dragon
cytosine arabinoside
Pogona vitticeps
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