In contrast to other game species and domestic livestock, there is a paucity of evidence concerning yields and thus meat obtained from the African savanna buffalo (Syncerus caffer caffer ). The aim of our study was to investigate the effects of age (categorized) and sex on buffalo carcass yields. Towards this goal, male (n = 17) and female (n = 13), and adult (n = 23) and subadult (n = 7) buffaloes were slaughtered, and the weight of the carcass and various organs/offal and six major muscles [(biceps femoris (BF), semimembranosus (SM), semitendinosus (ST), longissimus thoracis et lumborum (LTL), infraspinatus (IS) and supraspinatus (SS)] determined. Buffaloes had a high dressing percentage, calculated from the warm carcass weight, and with the heaviest muscle weights measured for the BF, SM and LTL muscles. Adults had heavier muscle weights than subadults, and all parameters except the heart and IS muscle weight differed significantly between these age groups. In addition, the skin and head weight differed significantly between males and females. In summary, African savanna buffalo yields (∼58%) compared favourably to other domestic animals, with the heavy weight of valuable muscles suggesting their commercial potential as a high-end value-added product.