ACE2 receptor expression in testes: implications in coronavirus disease 2019 pathogenesis†

Saguna Verma; Sarini Saksena; Hooman Sadri-Ardekani

doi:10.1093/biolre/ioaa080

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Saguna Verma,^1,*,** Sarini Saksena,² Hooman Sadri-Ardekani^3,4,*,**

¹Department of Tropical Medicine, Medical Microbiology, and Pharmacology, John A. Burns School of Medicine, University of Hawaii at Manoa, Honolulu, HI, USA
²Columbian College of Arts & Sciences, The George Washington University, DC, USA
³Wake Forest Institute for Regenerative Medicine, Winston-Salem, North Carolina, USA
⁴Department of Urology, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA

^*These authors contributed equally.
^**Correspondence: Department of Tropical Medicine, Medical Microbiology, and Pharmacology, John A. Burns School of Medicine, University of Hawaii at Manoa, Honolulu, HI 96822, USA. Tel:+18086921662; E-Mail: saguna@hawaii.edu or Wake Forest Institute for Regenerative Medicine, Wake Forest School of Medicine, Medical Center Boulevard, Winston-Salem, NC 27157, USA. Tel: +13367131493; E-mail: hsadri@wakehealth.edu

Abstract

Summary sentence

Expression of angiotensin-converting enzyme 2, receptor of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is high in the testes, therefore SARS-CoV-2 infection and its association with male reproductive health should be investigated in male coronavirus disease 2019 patients.

Citation Download Citation

Saguna Verma, Sarini Saksena, and Hooman Sadri-Ardekani "ACE2 receptor expression in testes: implications in coronavirus disease 2019 pathogenesis," Biology of Reproduction 103(3), 449-451, (19 May 2020). https://doi.org/10.1093/biolre/ioaa080

Published: 19 May 2020

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