The Endometrium as a Source of Mesenchymal Stem Cells for Regenerative Medicine1

Levent Mutlu; Demetra Hufnagel; Hugh S. Taylor

doi:10.1095/biolreprod.114.126771

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Levent Mutlu, Demetra Hufnagel, Hugh S. Taylor^*

^*Correspondence: Hugh S. Taylor, Yale School of Medicine, 310 Cedar Street, FMB 302, PO Box 208063, New Haven, CT 06520-8063. E-mail: hugh.taylor@yale.edu

Abstract

Stem cell therapies have opened new frontiers in medicine with the possibility of regenerating lost or damaged cells. Embryonic stem cells, induced pluripotent stem cells, hematopoietic stem cells, and mesenchymal stem cells have been used to derive mature cell types for tissue regeneration and repair. However, the endometrium has emerged as an attractive, novel source of adult stem cells that are easily accessed and demonstrate remarkable differentiation capacity. In this review, we summarize our current understanding of endometrial stem cells and their therapeutic potential in regenerative medicine.

Citation Download Citation

Levent Mutlu, Demetra Hufnagel, and Hugh S. Taylor "The Endometrium as a Source of Mesenchymal Stem Cells for Regenerative Medicine," Biology of Reproduction 92(6), (22 April 2015). https://doi.org/10.1095/biolreprod.114.126771

Received: 18 November 2014; Accepted: 1 April 2015; Published: 22 April 2015

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