Three taxa of succulent Crassulaceae: Two Echeveria, and one Sedum were found in the Southern Departments of Perú. (1) Echeveria peruviana, a species described 180 years ago, was not found until recently in its type locality, a full description is provided and more localities in the departments of Tacna and Moquegua are given. (2) Echeveria vulcanicola is a new species with conspicuous stems. It has only been found growing among black lava rocks in the Valley of the Volcanoes in Arequipa. (3) Sedum ignescens is a new species from Arequipa, Apurimac, Moquegua and Tacna, with leaves similar to Sedum andinum but with longer branches, its inflorescences and flowers are slightly smaller than those of Sedum reniforme but yellow with red spots instead of greenish white. Both Echeveria belong to series Racemosae. We consider all three species endemic to Southern Perú.