Three species of vascular plants and one hybrid are reported here as new to Alabama: (Lycopodium clavatum, Pterocaulon virgatum, Chrysopsis lanuginosa, and Asimina ×piedmontana). The Pterocaulon virgatum records represent the first collections of this species from east of the Mississippi River. The Chrysopsis lanuginosa record is the first for that species outside of Florida. Based on habitat, population size, and/or previous collections, all of these species are considered to be native to the flora of Alabama.