PANAS: Pipeline and a Case Study to Obtain Synonymous and Nonsynonymous Substitution Rates in Genes of Platyhelminthes

Víctor Caña-Bozada; Francisco N. Morales-Serna

doi:10.1654/COPA-D-22-00011

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Víctor Caña-Bozada,^1,* Francisco N. Morales-Serna²

¹Centro de Investigación en Alimentación y Desarrollo, A. C., Mazatlán 82112, Sinaloa, Mexico
²Instituto de Ciencias del Mar y Limnología, Universidad Nacional Autónoma de México, Mazatlán 82040, Sinaloa, Mexico

^*Corresponding author (victorcana1991@hotmail.com).

Abstract

Substitution rates in genes can provide information about their evolutionary dynamics and divergence among either species or protein groups. This work presents PANAS, a computational pipeline developed to facilitate the obtention of substitution rates in large amounts of genomic data from different taxa. We tested PANAS by analyzing the evolution of the mitochondrial protein-coding genes (PCGs) from 18 species of platyhelminths. Our results suggest that the cox1, cox2, cytb, and nad1 genes are under strong selection pressure at the nucleotide and protein level in platyhelminths.

Citation Download Citation

Víctor Caña-Bozada and Francisco N. Morales-Serna "PANAS: Pipeline and a Case Study to Obtain Synonymous and Nonsynonymous Substitution Rates in Genes of Platyhelminthes," Comparative Parasitology 90(1), 5-10, (7 February 2023). https://doi.org/10.1654/COPA-D-22-00011

Published: 7 February 2023

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