Red swamp crayfish Procambarus clarkii were collected from Cattail Marsh in Beaumont, Texas and necropsied. Eight (13%) of 62 crayfish collected were infected with metacercariae of Crepidostomum cornutum. Excysted metacercariae were stained and mounted for morphologic identification or preserved for molecular analysis. Morphometric values were consistent with those reported previously in the literature. Sequences of the 28S ribosomal RNA gene were aligned with the National Center for Biotechnology Information GenBank database. Blast analysis returned a result of 99% similarity for C. cornutum. This study provides the first report of C. cornutum metacercariae infecting P. clarkii in Texas substantiated by a voucher specimen and sequence data. Molecular data from this study should prove helpful in identification of adult stages from fish and cercariae from bivalves in future studies.