The efficacy of pesticides was evaluated against one of the important pests of coffee, Xylosandrus compactus and its associated fungus Ambrosia xylebori. Laboratory results revealed that insecticides Chlorpyrifos 50EC + Cypermethrin 5EC, Chlorpyrifos 20EC and Lambda-cyhalothrin 5EC alone and in combinations with all the tested fungicides caused 100 % mortality of adults at the tunnel entrance hole at higher dosages. However, mortality of stages inside the tunnel is limited to 52% for Chlorpyrifos 20EC + Cypermethrin 5 EC + Tebuconazole 25.9EC and this result is on par with Lambda-cyhalothrin 5EC + Tebuconazole 25.9EC with 50% mortality. Laboratory results on the efficacy of pesticides against the associated fungus, Ambrosia, showed that all fungicide doses significantly inhibited mycelial growth. Field experiments also exhibited similar results on the mortality of adults and the stages inside the coffee twigs. Chlorpyrifos 50EC + Cypermethrin 5EC and Lambda-cyhalothrin 5 EC in combination with fungicide Tebuconazole 25.9 EC also prevented new infestation up to 83% and 80% respectively even 45 days after spray applications.