Bryophytes contain a large number of terpenoids and aromatic compounds. In this article, the chemical constituents of selected liverworts collected in New Zealand, Malaysia, Madagascar, Argentina, Ecuador, and other southern hemispheric countries are discussed. The southern hemisphere is a region of extraordinarily high liverwort diversity. Many of compounds isolated from these liverworts have been represented by novel carbon skeletons and are important chemical markers of a liverwort's genus or family. Many of these compounds also have interesting biological activity.