A new species of Ptinus, collected in the Dominican Republic, is described and compared to the known West Indian fauna. The species is distinguished by the pronotum with 2 lateral spines and dorsally with 2 loose setal tufts medially on rounded protuberances, and an elytral setal pattern approximately in a triangular or heart-shaped outline. A checklist of the known West Indies Ptinidae (excluding the Anobiidae) is given.