Two recently discovered members of the South African genus Cleretum N.E.Br. are described: C. bruynsii Klak and C. patersonjonesii Klak. Cleretum bruynsii occurs along the edge of the winter-rainfall region, between Namaqualand and Bushmanland in the Northern Cape, from north-east of Springbok to the north-eastern edge of the Kamiesberg. This species is characterized by inconspicuous yellow flowers on short pedicels. Its sister species, C. patersonjonesii, is endemic to the Kamiesberg in Namaqualand and possesses large yellow flowers on long pedicels. The two new species are closely allied to C. schlechteri and C. papulosum from which they differ by their more papillate, spoon-shaped leaves and the absence of a false septum in the fruits. A key to the 14 species of Cleretum is provided.