The Great Lakes Indian Fish and Wildlife Commission produces consumption advisories for methylmercury in walleye (Sander vitreus) harvested by its member tribes in the 1837 and 1842 ceded territories of Michigan, Minnesota, and Wisconsin, USA. Lake-specific advice is based primarily on regressions of methylmercury concentrations on walleye length and incorporates standard reference doses to generate recommended meal frequencies. The effects of variability and uncertainty are directly incorporated into the consumption advice through confidence bounds for the general population and prediction bounds for the sensitive population. Advice is tailored to the needs of the tribes because harvest and consumption of fish are culturally important. Data were sufficient to provide consumption advice for 293 of the 449 lakes assessed. Most of these carried a recommendation of no more than 4 meals per month for the general population and no more than 1 meal per month for the sensitive population.