The Nantucket pine tip moth, Rhyaciona frustrana(Comstock), a common regeneration pest of loblolly pine, Pinustaeda L., has been shown to reduce tree volume yields throughlarval feeding. Chemical applications can be effective in protectingtrees from the growth losses associated with this feeding, and optimumspray timing values are commonly used to reduce the number of necessaryapplications and to increase insecticide efficacy. Optimal spray timingvalues for the Georgia Piedmont were obtained for the following fourinsecticides available for use in loblolly pine plantations: permethrin(Pounce), lambda-cyhalothrin (Warrior T), spinosad (SpinTor 2 SC), andBacillus thuringiensis variety kurstaki Berliner(Foray 48B). Optimal timing values were similar between the first andsecond generations for each of these compounds. All of the insecticidesused in this study significantly reduced tip moth damage below thecontrol treatment levels. Lambda-cyhalothrin was the most efficaciousand had the longest spray timing window. B. thuringiensiswas the least effective and had the shortest timing window. Spinosadand permethrin were similar in efficacy and spray timing values. Thisinformation is applicable to regions where there are three tip mothgenerations per year, as found in the southern Piedmont region and thecoastal plain of Virginia and most of North Carolina.