Birth of ng/fg Parthenogenetic Mouse

Tomohiro Kono

doi:10.1274/jmor.22.83

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Tomohiro Kono¹

¹Department of Bioscience, Faculty of Applied Bioscience, Tokyo University of Agriculture, Tokyo 156-8502, Japan

Abstract

In mammals, both maternal and paternal genomes are required to accomplish normal development to term, because parent-specific epigenetic modification of the genome is imposed during gametogenesis. This leads to inequivalent expression of imprinted genes sorely from the maternal and paternal allele. Production of a viable parthenogenetic mouse individual proved that genomic imprinting governs mammalian ontogeny.

Citation Download Citation

Tomohiro Kono "Birth of ng/fg Parthenogenetic Mouse," Journal of Mammalian Ova Research 22(2), 83-86, (1 April 2005). https://doi.org/10.1274/jmor.22.83

Published: 1 April 2005