Possibility of Clinical Application of Preimplantation Genetic Screening Following Blastomere Biopsy in Infertility Treatments

Yukiko Katagiri; Yusuke Fukuda; Mamoru Kitamura; Yuka Sasaki; Naoki Takeshita; Mineto Morita

doi:10.1274/jmor.26.207

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Yukiko Katagiri,^1,2,* Yusuke Fukuda,^1,2 Mamoru Kitamura,^1,2 Yuka Sasaki,² Naoki Takeshita,^1,2 Mineto Morita^1,2

¹1Department of Obstetrics and Gynecology
²2Reproduction Center, OB/GYN, Toho Medical Center, Omori Hospital, Toho University, 6-11-1 Omori-Nis

^*To whom correspondence should be addressed. e-mail: yukikonk@med.toho-u.ac.jp

Abstract

Preimplantation diagnosis (PGD) has been performed for sex-linked inherited diseases since 1990, and it has also been utilised in Japan. In other countries, Preimplantation Genetic Screening (PGS) has been introduced to reduce pregnancies with aneuploidies. It is useful for diagnosing inherited diseases and reciprocal translocation of early embryos. However, its indication and effectiveness for cases of habitual abortion, advanced maternal age, and repetitive reproductive failure should continue to be a matter of concern.

Citation Download Citation

Yukiko Katagiri, Yusuke Fukuda, Mamoru Kitamura, Yuka Sasaki, Naoki Takeshita, and Mineto Morita "Possibility of Clinical Application of Preimplantation Genetic Screening Following Blastomere Biopsy in Infertility Treatments," Journal of Mammalian Ova Research 26(4), 207-213, (1 October 2009). https://doi.org/10.1274/jmor.26.207

Published: 1 October 2009