Preimplantation diagnosis (PGD) has been performed for sex-linked inherited diseases since 1990, and it has also been utilised in Japan. In other countries, Preimplantation Genetic Screening (PGS) has been introduced to reduce pregnancies with aneuploidies. It is useful for diagnosing inherited diseases and reciprocal translocation of early embryos. However, its indication and effectiveness for cases of habitual abortion, advanced maternal age, and repetitive reproductive failure should continue to be a matter of concern.
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1 October 2009
Possibility of Clinical Application of Preimplantation Genetic Screening Following Blastomere Biopsy in Infertility Treatments
Yukiko Katagiri,
Yusuke Fukuda,
Mamoru Kitamura,
Yuka Sasaki,
Naoki Takeshita,
Mineto Morita
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Journal of Mammalian Ova Research
Vol. 26 • No. 4
October 2009
Vol. 26 • No. 4
October 2009
Abortion
Ageing
PGD
PGS
translocation