This case report describes a successful delivery after cryopreservation of a human day-7 blastocyst. A 36-year-old woman, after failed stimulation and cryopreserved-warmed cycles, underwent antagonist-treatment protocol stimulation, and oocytes were recovered transvaginally with ultrasound guidance. Nine mature oocytes were obtained and eight were fertilized by ICSI. A single blastocyst was transferred on day 5, but no implantation occurred. On day 7, one of the non-transferred embryos developed into a blastocyst and was vitrified using a Cryotop procedure. Two months after the previous retrieval cycle, the cryopreserved day-7 blastocyst survived the warming process and was transferred to the patient's uterus. The woman became pregnant and delivered a healthy female.
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1 April 2012
Case Report: A Successful Delivery Following the Transfer of a Cryopreserved Human Day-7 Blastocyst
Yasuko Matsumura,
Chiaki Kiriake,
Tomoe Tamaki,
Kenichiro Hiraoka,
Hirofumi Uto,
Hiroyuki Yoshida,
Seiji Kitamura
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Journal of Mammalian Ova Research
Vol. 29 • No. 2
April 2012
Vol. 29 • No. 2
April 2012
blastocyst
cryopreservation
Day-7
human
vitrification