The fragility of ecosystem health has become a key factor hindering the sustainable development of the ecological environment. Through a review of published research from domestic and foreign scholars, starting from the endogenous logic of studies in the field of ecosystem vulnerability (EV), this paper sorts out the literature on the aspects of measurement models, prediction methods and risk assessment, comprehensively defines the research category and scientific framework of EV, and analyzes the research ideas and development trends. We arrived at the following conclusions: 1) The connotation of ecosystem vulnerability not only embodies the change in the vulnerability of the natural environment, but it also reflects the irreversible damage to the ecosystem caused by excessive development and industrial production activities. 2) The setting of ecosystem vulnerability indices should aim to fully reflect the essential features of that vulnerability, which should include the index systems of natural, social, economic and other related factors. 3) There are many types of ecosystem vulnerability measurement methods, prediction models and risk evaluation models, which have different focuses and advantages. The most appropriate method should be adopted for conducting comprehensive and systematic evaluation, prediction and estimation according to the different representation and evolution mechanisms of the chosen research object and regional ecosystem vulnerability. 4) Based on the regional system characteristics, corresponding risk management measures should be proposed, and pertinent policy suggestions should be put forward to improve the ecological safety and sustainable development of an ecologically vulnerable area.