Stormwater catch basins are the primary source of mosquitoes targeted by the North Shore Mosquito Abatement District, in the northern suburbs of Chicago. Over a 17-wk period (June to September 2011), 3 clusters of catch basins located within a 0.7-km² area were monitored weekly with dipper samples of immature mosquitoes. During the 2nd week of monitoring, Natular™ XRT tablets (6.25% spinosad) were applied to northernmost cluster and FourStar™ Briquets (6% Bacillus sphaericus, 1% Bacillus thuringiensis israelensis) were applied to the southernmost cluster; the remaining middle cluster was kept untreated. Following 15 wk of monitoring in 20 basins in each cluster, both Natular and FourStar reduced immature numbers in treated catch basins for 8 consecutive weeks. These results suggest, if effectively timed, a single application of either larvicide may last an entire season.