Five seasons of survey and excavation in Port Joli Harbour, NS, Canada, have resulted in a high-resolution archaeofaunal sample from 2 contrasting shell-bearing sites: AlDf-24, and AlDf-30 (Jack's Brook). In this paper, we discuss the evidence for differences in mollusk-, fish-, and mammal-harvesting strategies between contemporaneously occupied sites. Furthermore, we highlight shifts in Mi'kmaw exploitation of coastal resources around the Middle to Late Maritime Woodland transition (ca. 1300 cal B.P.). Finally, we present insights regarding shellfish-harvesting strategies and site seasonality from isotopic analysis of softshell clam (Mya arenaria) shells. In the process, we construct a history of human—animal relationships in Port Joli, and reveal crucial similarities and important differences with Wabanaki economic strategies in adjacent regions.