Translator Disclaimer
1 January 1990 Ineffectiveness and Comparative Pathogenicity of Attenuated Rabies Virus Vaccines for the Striped Skunk (Mephitis mephitis)
Author Affiliations +
Abstract

Three attenuated rabies virus vaccines (SAD-B19, ERA/BHK-21, AZA 2) were compared for efficacy and safety in the striped skunk (Mephitis mephitis) by the oral and intranasal routes. The SAD-B19 and ERA/BHK-21 vaccines were given orally; all three vaccines were given intranasally. Oral administration of SAD-B19 and ERA/BHK-21 vaccines induced neither seroconversion nor significant protection against rabies challenge. One skunk which consumed a SAD-B19 vaccine-laden bait succumbed to vaccine-induced rabies. Intranasal instillation of the three vaccines resulted in the deaths of two of six (AZA 2), three of six (ERA/BHK-21) and six of six (SAD-B19) skunks.

Rupprecht, Charlton, Artois, Casey, Webster, Campbell, Lawson, and Schneider: Ineffectiveness and Comparative Pathogenicity of Attenuated Rabies Virus Vaccines for the Striped Skunk (Mephitis mephitis)
C. E. Rupprecht, K. M. Charlton, M. Artois, G. A. Casey, W. A. Webster, J. B. Campbell, K. F. Lawson, and L. G. Schneider "Ineffectiveness and Comparative Pathogenicity of Attenuated Rabies Virus Vaccines for the Striped Skunk (Mephitis mephitis)," Journal of Wildlife Diseases 26(1), 99-102, (1 January 1990). https://doi.org/10.7589/0090-3558-26.1.99
Received: 5 June 1989; Published: 1 January 1990
JOURNAL ARTICLE
4 PAGES


SHARE
ARTICLE IMPACT
Back to Top