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1 May 2010 Bispectral Index Analysis of Opioid Immobilization of Rocky Mountain Elk
Terry J. Kreeger, Khursheed Mama, Matthew Huizenga, Cole Hansen, Cynthia Tate
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Abstract

We immobilized elk with either isoflurane to produce general anesthesia (control), 0.01 mg/kg carfentanil plus 0.1 mg/kg xylazine, or 0.25 mg/kg butorphanol plus 0.4 mg/kg azaperone plus 0.15 mg/kg medetomidine (BAM) and measured the bispectral index (BIS). The carfentanil-xylazine BIS (70.4 ± 1.4) and the BAM BIS (60.2 ± 1.5) were higher than the control BIS (47.2 ± 4.1; P ≤ 0.001). These data indicate that opioids produce neuroleptanalgesia and not general anesthesia or sedation, which explains observed elk responses to these drugs.

Terry J. Kreeger, Khursheed Mama, Matthew Huizenga, Cole Hansen, and Cynthia Tate "Bispectral Index Analysis of Opioid Immobilization of Rocky Mountain Elk," Journal of Wildlife Management 74(4), 902-905, (1 May 2010). https://doi.org/10.2193/2009-286
Published: 1 May 2010
JOURNAL ARTICLE
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KEYWORDS
Anesthesia
azaperone
bispectral index
butorphanol
carfentanil
Cervus elaphus
isoflurane
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