A juvenile orangutan (Pongo pygmaeus pygmaeus) died after 8 days of diarrhea and vomiting. Necropsy showed petechial hemorrhages in the skin, the myocardium, and the peritoneal membranes. The lungs were hyperemic and edematous, and the liver and spleen were enlarged. Histologic changes consisted of interstitial pneumonia, hepatitis, and splenic hyperplasia. Numerous eosinophilic intranuclear inclusion bodies were visible in pulmonary epithelial cells, hepatocytes, and splenic endothelial cells. Electron microscopic examination revealed herpesvirus in hepatocyte nuclei. Polymerase chain reaction of liver tissue demonstrated the presence of a herpes simplex virus–1.
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1 March 2005
HERPES SIMPLEX INFECTION IN A JUVENILE ORANGUTAN (PONGO PYGMAEUS PYGMAEUS)
Maria J. L. Kik,
Jan H. Bos,
Jan Groen,
Gerry M. Dorrestein
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Journal of Zoo and Wildlife Medicine
Vol. 36 • No. 1
March 2005
Vol. 36 • No. 1
March 2005
Herpes simplex virus–1
human herpesvirus 1
orangutans
Pongo pygmaeus pygmaeus