A 17-yr-old female fallow deer presented with ataxia, inappetence, decreased fecal output, and decreased mentation. A complete blood count demonstrated leukocytosis (24.1 × 103/μl, n = 1.16–7.38 × 103/μl), characterized by lymphocytosis (22.89 × 103/μl, n = 0.18–3.65 × 103/μl), anemia (packed cell volume 20%, n = 29.0–55.8%), decreased red blood cell count (4.1 × 103/μl, n = 6.86–14.72 × 103/μl), and decreased hemoglobin (7.5 g/dl, n = 9.4–19.2 g/dl). Numerous mature, well-differentiated lymphocytes were noted on the blood film. Despite treatment and clinical improvement, the decision was made to euthanize the deer. Histopathology identified a monomorphic population of CD3 positive, CD79a negative small lymphocytes replacing most of the hematopoietic tissue in the bone marrow without evidence of tissue invasion. Results of viral screening were negative.
How to translate text using browser tools
1 September 2015
T-CELL LYMPHOCYTIC LEUKEMIA IN A FALLOW DEER (DAMA DAMA)
Wm. Kirk Suedmeyer,
Brian G. Stockinger,
Michael M. Garner,
Daniel S. Bradway,
Charlotte Hollinger,
Matti Kiupel
ACCESS THE FULL ARTICLE
bovine leucosis virus
epizootic hemorrhagic disease virus
fallow deer (Dama dama)
lymphocytic leukemia
T lymphocytes