Translator Disclaimer
16 December 2021 CANINE DISTEMPER AND PARVOVIRUS VACCINATION WITH RECOMBITEK C3 IN AFRICAN WILD DOGS (LYCAON PICTUS)
Lauren M. Mulreany, Andrew C. Cushing, Edward C. Ramsay
Author Affiliations +
Abstract

Infectious disease threats are increasingly recognized as a major contributor to mortality in wild populations of African wild dog (Lycaon pictus, AWD). Canine distemper virus (CDV) infection has been implicated as a cause of pack mortality in both captive and wild AWD populations. Ten animals were vaccinated with RecombitekTM C3, a vaccine containing a recombinant CDV, and modified live canine parvovirus (CPV) and adenovirus-2 components, at 8, 12, and 16 wk of age. Half of the pups received the vaccine IM and the other half SC. All ten pups had a positive serological response to CDV after the second vaccination, which decreased or stagnated after the third vaccination. Half of the pups had CDV titers ≥32 at 20 wk of age. Titers to CPV were high in all pups prior to vaccination and dropped precipitously over the course of the vaccine series. At the last sampling period, only 50% of the pups had measurable CPV titers. An initially higher titer was seen for CDV in the IM administration group; however, this was not significant at later time points. Vaccination with Recombitek C3 appears to be safe and effected a sustained serological response to CDV in AWD.

Copyright 2021 by American Association of Zoo Veterinarians
Lauren M. Mulreany, Andrew C. Cushing, and Edward C. Ramsay "CANINE DISTEMPER AND PARVOVIRUS VACCINATION WITH RECOMBITEK C3 IN AFRICAN WILD DOGS (LYCAON PICTUS)," Journal of Zoo and Wildlife Medicine 52(4), 1229-1233, (16 December 2021). https://doi.org/10.1638/2021-0004
Accepted: 4 July 2021; Published: 16 December 2021
JOURNAL ARTICLE
5 PAGES


Share
SHARE
ARTICLE IMPACT
RIGHTS & PERMISSIONS
Get copyright permission
Back to Top