Histura perseavora Brown, new species, from Guatemala, is described and illustrated. It is compared with Histura curvata (Meyrick) from Brazil and Histurodes costaricana Razowski from Costa Rica. All specimens of H. perseavora were reared from either fruit, fruit pedicels, or young green branches of avocados (Persea americana Mill.; Lauraceae) during efforts to identify lepidopteran pests of this commodity in Guatemala. Coincidentally, we discovered museum specimens of H. costaricana reared from avocados in Costa Rica. We present a brief review of the fragmentary knowledge of the larval stages of Polyorthini, the tribe to which H. perseavora is assigned.