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1 May 2007 Possible Combined Effects of 900 MHZ Continuous-Wave Electromagnetic Fields and Gentamicin on the Auditory System of Rats
Marta Parazzini, Paolo Galloni, Marta Piscitelli, Rosanna Pinto, Giorgio A. Lovisolo, Gabriella Tognola, Paolo Ravazzani, Carmela Marino
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Abstract

Parazzini, M., Galloni, P., Piscitelli, M., Pinto, R., Lovisolo, G. A., Tognola, G., Ravazzani, P. and Marino, C. Possible Combined Effects of 900 MHZ Continuous-Wave Electromagnetic Fields and Gentamicin on the Auditory System of Rats. Radiat. Res. 167, 600–605 (2007).

The aim of this study was to evaluate the cochlear functionality of Sprague-Dawley rats exposed to electromagnetic fields at 900 MHz and to gentamicin by distortion product otoacoustic emissions, which are a well-known indicator of the status of the cochlea's outer hair cells. A population of 32 rats was divided into four groups: group 1 was treated with daily intramuscular injections of 150 mg/kg body weight gentamicin for 15 days; group 2 was treated with daily intramuscular injections of 150 mg/kg body weight gentamicin for 15 days and exposed to electromagnetic fields; group 3 was exposed to electromagnetic fields; group 4 was sham-exposed. Rats were exposed 2 h/day, 5 days/week for 4 weeks at a local SAR of 4 W/kg in the ear (continuous wave at 900 MHz). Distortion product otoacoustic emissions tests were carried out before, during and after the combined exposure. The analysis of the data showed no subchronic exposure to electromagnetic fields on the inner auditory system of rats in either normal ears or ears exposed to a well-recognized pathological agent.

Marta Parazzini, Paolo Galloni, Marta Piscitelli, Rosanna Pinto, Giorgio A. Lovisolo, Gabriella Tognola, Paolo Ravazzani, and Carmela Marino "Possible Combined Effects of 900 MHZ Continuous-Wave Electromagnetic Fields and Gentamicin on the Auditory System of Rats," Radiation Research 167(5), 600-605, (1 May 2007). https://doi.org/10.1667/RR0779.1
Received: 25 August 2006; Accepted: 1 December 2006; Published: 1 May 2007
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