Translocation of wildlife is a valuable tool for managers to alleviate impacts of human/wildlife conflicts, habitat fragmentation, and small population sizes. Pelecanus occidentalis (Brown Pelican) were previously successfully translocated into Louisiana in 1960–1980s and had rebounded significantly prior to the Deepwater Horizon Oil Spill in April 2010. The Deepwater Horizon Oil Spill had a dramatic impact on southeastern Louisiana, including the people, wildlife, and coastal habitats of the region. We translocated 182 oil-rehabilitated Brown Pelicans from southeastern Louisiana to an area non-impacted by the oil spill in southwestern Louisiana (Rabbit Island, Cameron Parish). Daily surveys were conducted at the island for six weeks and documented mortality, movements, integration with local pelican flocks, persistence of pelicans at the island, and the role of supplemental feeding. We documented no mortality of rehabilitated birds and found that translocated Brown Pelicans readily integrated with local pelican flocks. Supplemental feeding likely contributed to the persistence of pelicans at Rabbit Island from weeks 1 to 4. By weeks 4 to 6, many local and translocated pelicans moved away from the island, likely due to a combination of natural and human-induced factors. After the initial stages of the translocation, we tentatively suggest that the program was a success and propose recommendations for future translocation attempts with Brown Pelicans.