Insecticides negatively impact predators. The effect of insecticides on functional response of sevenspotted lady beetle, Coccinella septempunctata L., to melon aphid, Aphis gossypii Glover, was studied at controlled laboratory conditions of 26 ± 2°C, 65 ± 5% relative humidity, and photoperiod of 16:8 light:dark hours. In response to insecticides, all stages of C. septempunctata had Type II functional response, whereas Type III was observed for third, fourth, and adult stages in the check treatment. Least handling time, high attack rate, and greatest theoretical maximum predation were found with buprofezin in 1^st instar (0.098±1.461h, 1.179±0.051 h^-1, 244.90), 2^nd instar (0.04±0.278h, 0.404±0.008h^-1, 600.00), 3^rd instar (0.032±0.313h, 1.182±0.060h^-1, 750.00), 4^th instar (0.028±0.14h, 2.704±0.005h^-1, 857.14) and adult (0.031±0.159h, 1.137±0.159h^-1, 774.19) followed by pymetrozine. To evaluate the impact of insecticide on C. septempunctata at field conditions, selected insecticides were sprayed on C. septempunctata feeding on A. gossypii on chili, Capsicum annuum L. Fewest C. septempunctata were observed with buprofezin 55±3.56%, 65±8.97%, 85±6.56% and pymetrozine 32±4.45%, 71±10.12%, 84±7.54% at 24, 72, and 240 hours after spraying.