The present study is based on oribatid mite material collected from Mayotte island (Comoro Islands, Ethiopian region) in 2011–2016. A new species of the genus Uracrobates (Oribatida, Mochlozetidae) is described; Uracrobates (Uracrobates) mayottensissp. nov. differs from all species of the nominative subgenus by having a rounded rostrum (versus bidentate or pointed). An updated generic diagnosis and an identification key to the known subgenera and species of Uracrobates are presented. A list of all oribatid mite taxa of the Comoro Islands, including 41 species, 30 genera and 19 families, is provided. The genus Phauloppia and the species Edwardzetes novazealandicus are recorded in the Ethiopian region for the first time.