The 22 species of Opiliones recorded from Iran are known from four families: one species of Dicranolasmatidae, five species of Nemastomatidae, 15 species of Phalangiidae, and a single species of Sclerosomatidae. Five of these are recorded for the first time from the country: Dicranolasma ponticum Gruber, 1998, Opilio nabozhenkoi Snegovaya, 2010, Phalangium armatum Snegovaya, 2005, Phalangium kopetdaghensis Tchemeris & Snegovaya, 2010, and Graecophalangium karakalensis Tchemeris & Snegovaya, 2010. An additional unnamed Rilaena species is known from the literature, but not included in the total number of species from the country. One new genus and two new species are illustrated and described as new from Iran. The new species are Opilio kakunini and Rilaena kasatkini. Goasheer, a new genus, is described to hold the species “Homolophus” iranus Roewer, 1952.