Turkey Vultures (Cathartes aura) in southern and south-central Saskatchewan first nested in deserted houses in 1982. This new behavior across the Aspen Parkland and Boreal Transition ecoregions became more common in the mid-1990s as vultures increased and occupied new territory. We documented 126 nestings, which produced 185 young in 74 deserted buildings during 2003–2006. The mean number of young fledged per successful nest (1.7) was similar to that recorded in other parts of its range.