We monitored one female hack-released Osprey (Pandion haliaetus) across her lifespan and identified her migration routes over a 4-year period (2002–2006) using satellite radiotelemetry. We documented the recruitment of this bird into the breeding population and her lifetime reproductive success. This Osprey was raised at Big Muskego Lake in southeast Wisconsin, wintered at Lake Bayano in Panama (3,877 km south-southeast [163°] of Big Muskego Lake), and nested near St. Paul, Minnesota (4,183 km north-northwest [343°] of Lake Bayano and 446 km northwest [300°] of Big Muskego Lake). The lifespan of this female was 5 years, 5 months, and her lifetime reproductive success was three young over a period of 3 years, 2005–2007, as a breeder. Migration routes of this individual Osprey changed over her lifespan; these changes may have been influenced by weather.