The invertebrate fauna of the Mississippi River is compiled from published material (215 total taxa) is compiled from published material (205 taxa) and records of 10 new taxa obtained in a dietary study of sturgeon in the Lower Mississippi River. The previously undocumented taxa are Leptophlebia sp. (Ephemeroptera: Leptophlebiidae), Pseudiron centralis McDunnough (Ephemeroptera: Pseudironidae), Gillotia sp. (Diptera: Chironomidae), Lipiniella sp. (Diptera: Chironomidae), Metriocnemus fuscipes (Meigen) (Diptera: Chironomidae), Parachironomus sp. (Diptera: Chironomidae), Paratendipes basidens Townes (Diptera: Chironomidae), Polypedilum flavum (Johannsen) (Diptera: Chironomidae), Saetheria sp. (Diptera: Chironomidae), and Zavrelia sp. (Diptera: Chironomidae).