We present an annotated list of 22 species of blow flies (Diptera: Calliphoridae) and one species of cluster flies (Polleniidae) known from the state of Mississippi, with one additional blow fly species likely to occur there based on a record in neighboring Alabama. New state records include five species from the subfamily Calliphorinae: Angioneura flavescens (Reinhard), Angioneura obscura (Townsend), Opsodexia bicolor (Coquillett), and Opsodexia nox (Downes), and Lucilia eximia (Wiedemann). The number and density of taxa per 100,000 km² is consistent with that of blow fly taxa recorded for other states across the contiguous United States.