The goblin spider genus Simonoonops Harvey has been known only from its Venezuelan type species, but the group occurs also in Guyana and the Lesser Antilles. Most of its members have been misplaced in the genus Dysderina Simon; D. princeps Simon, D. spinigera Simon, D. craneae Chickering, D. globina Chickering, D. soltina Chickering, and D. zinona Chickering are transferred to Simonoonops. Members of Simonoonops resemble those of Dysderina in having three transverse ridges on the sternum, but differ in lacking a groove connecting the anterior spiracles and having a more complex embolic region on the male palp. Two specific names are newly synonymized: S. orghidani (Dumitrescu and Georgescu) with S. craneae, and S. zinona with S. soltina. Six new species are described: S. simoni, S. grande, and S. andersoni from Venezuela, S. lutzi from Guyana, S. etang from Grenada, and S. chickeringi from Saint Vincent.