BioOne.org will be down briefly for maintenance on 17 December 2024 between 18:00-22:00 Pacific Time US. We apologize for any inconvenience.
How to translate text using browser tools
1 March 2008 INTERPOPULATION HYBRID BREAKDOWN MAPS TO THE MITOCHONDRIAL GENOME
Abstract

Hybrid breakdown, or outbreeding depression, is the loss of fitness observed in crosses between genetically divergent populations. The role of maternally inherited mitochondrial genomes in hybrid breakdown has not been widely examined. Using laboratory crosses of the marine copepod Tigriopus californicus, we report that the low fitness of F3 hybrids is completely restored in the offspring of maternal backcrosses, where parental mitochondrial and nuclear genomic combinations are reassembled. Paternal backcrosses, which result in mismatched mitochondrial and nuclear genomes, fail to restore hybrid fitness. These results suggest that fitness loss in T. californicus hybrids is completely attributable to nuclear–mitochondrial genomic interactions. Analyses of ATP synthetic capacity in isolated mitochondria from hybrid and backcross animals found that reduced ATP synthesis in hybrids was also largely restored in backcrosses, again with maternal backcrosses outperforming paternal backcrosses. The strong fitness consequences of nuclear–mitochondrial interactions have important, and often overlooked, implications for evolutionary and conservation biology.

"INTERPOPULATION HYBRID BREAKDOWN MAPS TO THE MITOCHONDRIAL GENOME," Evolution 62(3), 631-638, (1 March 2008). https://doi.org/10.1111/j.1558-5646.2007.00305.x
Received: 13 August 2007; Accepted: 7 November 2007; Published: 1 March 2008
JOURNAL ARTICLE
8 PAGES

This article is only available to subscribers.
It is not available for individual sale.
+ SAVE TO MY LIBRARY

KEYWORDS
Copepod
intergenomic coadaptation
intrinsic postzygotic isolation
mitochondrial function
nuclear–mitochondrial epistasis
RIGHTS & PERMISSIONS
Get copyright permission
Back to Top