With the continuous growth of China′s national economy, the people′s spiritual and cultural consumption needs are strong. Cultural and leisure venues are one of the most important spaces for meeting people's increasing needs for a better life. Taking 5625 cultural and leisure venues in Beijing as the research object, we analyzed the spatial and temporal distribution characteristics of the cultural and leisure venues in Beijing from 1994–2019, and the factors influencing them, by using the analysis methods of barycentric coordinates, standard deviation ellipse, kernel density analysis, spatial autocorrelation and Geodetector. The results show four main aspects of this system. (1) The spatial distribution of cultural and leisure venues in Beijing is uneven and shows a “core-edge” pattern. In the long run, there has been a tendency for cultural and leisure venues to spread into the northern and southern suburbs. (2) Beijing's cultural and leisure venues have evolved from a “single-core cluster” in the central city to a “dual-core coexistence” in both the central city and Tongzhou District, in addition to a spatial trend of spreading throughout the whole city. (3) Located in the central city, Xicheng, Dongcheng, Chaoyang and Fengtai form the HH agglomeration of cultural and leisure venues in Beijing, while Huairou and Miyun constitute the LL agglomeration. (4) The spatial distribution of cultural and leisure venues in Beijing is affected by many factors, such as the economy, population, transportation, education and policies, and the main driver is changing from a combination of “economy” and “demand” to the single factor of “economy”.