A disease resembling thiamine-responsive polioencephalomalacia of domestic ruminants is described in four wild pronghorn from Saskatchewan. One animal was found dead, two were recumbent and unable to rise and the fourth was staggering and ataxic. Lesions were confined to the brain and consisted of brain swelling with herniation, symmetrical hemorrhagic foci in the thalamus and brainstem, and laminar necrosis of cortical neurons. All animals had been eating grain prior to their death. Possible pathogenetic mechanisms including changes in rumen microflora resulting in thiamine deficiency, plant and salt intoxication are discussed.
You have requested a machine translation of selected content from our databases. This functionality is provided solely for your convenience and is in no way intended to replace human translation. Neither BioOne nor the owners and publishers of the content make, and they explicitly disclaim, any express or implied representations or warranties of any kind, including, without limitation, representations and warranties as to the functionality of the translation feature or the accuracy or completeness of the translations.
Translations are not retained in our system. Your use of this feature and the translations is subject to all use restrictions contained in the Terms and Conditions of Use of the BioOne website.