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1 July 1988 Preliminary Evaluation of Praziquantel Against Metacercariae of Nanophyetus salmincola in Chinook Salmon (Oncorhynchus tshawytscha)
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Abstract

Praziquantel at dosages of 10, 20 or 100 mg/kg of body weight was evaluated against metacercariae of Nanophyetus salmincola in chinook salmon (Oncorhynchus tshawytscha). Ten salmon were used in each of four treated groups and 10 salmon were nontreated controls. Three wk after treatment, viability of metacercariae was determined by histologic evaluation, and by feeding the salmon to coyotes and subsequently determining the numbers of trematode eggs/g of feces and numbers of N. salmincola recovered at necropsy. Results of the experiment indicated that praziquantel at the dosages and routes of administration used was not effective against metacercariae in chinook salmon.

Foreyt and Gorham: Preliminary Evaluation of Praziquantel Against Metacercariae of Nanophyetus salmincola in Chinook Salmon (Oncorhynchus tshawytscha)
William J. Foreyt and John R. Gorham "Preliminary Evaluation of Praziquantel Against Metacercariae of Nanophyetus salmincola in Chinook Salmon (Oncorhynchus tshawytscha)," Journal of Wildlife Diseases 24(3), 551-554, (1 July 1988). https://doi.org/10.7589/0090-3558-24.3.551
Received: 24 November 1987; Published: 1 July 1988
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