A bobcat (Felis rufus) estimated to be 6-mo old exhibited head pressing, stupor, intermittent seizures, and vocalization. Based on gross and histopathologic features, it was diagnosed to have severe focally extensive protozoal meningoencephalitis. Toxoplasma gondii was confirmed as the etiologic agent by an avidinbiotin immunohistochemical test. This is the first report of clinical toxoplasmosis in a free-ranging bobcat.
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