We describe collaborative archaeological research on caribou hunting sites in the homeland of the Shúhtagot'ine in the central Mackenzie Mountains of Canada's Northwest Territories. Shúhtagot'ine Elders and cultural resource managers are working together to investigate important cultural places that are at risk of destruction from climate-driven landscape changes. We use 3 case studies to illustrate how knowledge production in the context of long-term, place-based research has led to key insights about ancestral caribou hunting sites, including perennial alpine ice patches and wood hunting structures, and how that knowledge is being mobilized to help conserve important values in the Shúhtagot'ine cultural landscape. Archaeological research promotes the sustainability of Indigenous cultural landscapes through the preservation of cultural heritage, via the recall of “landscape memories,” and by unlocking archives of ancient biological material. The process of knowledge coproduction is mutually beneficial for all participants, especially when Indigenous Elders and youth are brought together in fieldwork settings.